RNA Details
Disease Name
acute kidney injury
Tissue
kidney
RNA Symbol
mir-146
RNA ID
MI0000170
RNA Type
miRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
NA
Target
HMGA2
Pathway
CHEMOKINE SIGNALING PATHWAY
PubMed ID
27444565
Title
MicroRNA-146a in Human and Experimental Ischemic AKI: CXCL8-Dependent Mechanism of Action
Year
2017
Function
"miR-146a is a key mediator of the renal tubular response to iri that limits the consequences of inflammation, a key process in the development of acute kidney injury (AKI) and chronic kidney disease (CKD)."